Clarity in cell line development

Important considerations for optimising outgrowth from single cells in cloning plates during cell line development

When developing biotherapeutics there are many parts of the process that require optimisation. Cell line development is a key part of this process and there are many aspects where changes can have a dramatic effect on timelines and outcomes. One key area which is challenging to many of our customers is outgrowth of clones in …

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Collaboration: changing CLD practices

In January 2019 Solentim, a global leader in cell line development (CLD) instrumentation, and bioengineering company ATUM, announced a technology partnering and collaboration agreement to enable rapid, high expression, stable cell line development. But what exactly are the tangible benefits gained from both parties and for customers, and why does this fusion of technology offer more …

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Finding the right balance: digital biology versus smart, transformative automation

In this latest blog by Solentim’s Dr Ian Taylor, the advent of digital biology is discussed. This is compared and contrasted with smarter automation, transformative new biology and better control over proven wet biology methods which have been developed and refined over decades. Many agree that this is the era of synthetic biology, smarter automation …

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Why is a clonally pure cell line so important in CRISPR research?

Never far from scientific and mainstream news, CRISPR is regularly hailed as one of the most important scientific discoveries of our time. With potential applications across wide-ranging fields from medicine to agriculture, being able to control gene expression could provide treatments for a number of genetic diseases and solve global food shortages in times of …

Read more Why is a clonally pure cell line so important in CRISPR research?