The Award Winning New Measure of IgG Titer for Automated Cell Counting - Increase Productivity in Cell Line Development

From static stage to expansion and beyond, ICON™ is a world’s first. A benchtop system for cell line development and protein science, automated cell counting and IgG titer measurements all on one platform, plus reporting on normalized titer for the characterization of high productivity clones in cell line development

Winner of the SLAS New product Award, ICON offers low-volume measurements of critical cell quality attributes; IgG titer, confluency, cell number and viability cell density assessing productivity to enable rapid stratification of leading candidates.

All of this in one compact instrument!

  1. Rapid 96 well plate IgG Titer Measurements (from 2.5 to 1500 mg/L)
  2. High Accuracy Confluency
  3. In-Plate Cell Number (static plate cell count)
  4. Automated Cell Counting + Viability (for 1 - 24 samples)
  5. Microscope Mode (brightfield and fluorescent image capture)

Helping scientists focus on the winners, ICON enhances success through meaningful data.


Viewing CHO cell productivity by normalized titer

ICON combines IgG titer assays with cell number and cell counting, enabling measures of specific productivity for both the static and expansion stages of cell line development.

 

ICON Plate-Based Titer

For cloning and expansion stages

  • Rapid 96 well plate IgG titer measurements
  • Uses just 60 µL sample
  • Wide detection range

ICON Plate-Based Cell Number

For cloning plate stage

  • Rapid scanning
  • High accuracy algorithm
  • For 96 and 384 well plates

ICON Automated Viable Cell Counting

For expansion cell stage

  • Trypan blue and AO/PI measurements
  • From 1 to 24 counts per run
IgG titer measurements and cell counting in a 96 well plate - to make normalised titer

ICON from Solentim, an award-winning instrument for IgG titer measurements and automated cell countingSolentim wins New Product Award at SLAS 2021

Solentim is delighted to have won a New Product Award from the Society for Laboratory Automation and Screening (SLAS), announced this week at SLAS Digital 2021.

  • Manage: User management hierarchy including inbuilt user training course.
  • HISTORYTREE™: Displays multiple data points from a clone’s history along a unique graphical timeline.
  • Sort: Rapid filtering of per-cell data to characterize lead candidates.
  • Report: Draws on system and service status within final report as evidence of quality process.
  • Operates Continuous Audit Mode supporting requirements to achieve 21 CFR part 11 and EU Annex 11 compliance

Solentim STUDIUS – reporting on cell line development data to assess clone productivity for characterisation of lead candidates

Trypan-stained CHO cells for viability counting

Microscope Mode

High clarity microscopy for cell counting and single cell line development

ICON Microscope Mode offers cell line development scientists a convenient set of tools for viewing and the capture of cellular images. Ideally suited for quick review and confirmation of cell morphology and fluorescent expression of RFP and GFP signals.