Clarity in cell line development

Finding the right balance: digital biology versus smart, transformative automation

In this latest blog by Solentim’s Dr Ian Taylor, the advent of digital biology is discussed. This is compared and contrasted with smarter automation, transformative new biology and better control over proven wet biology methods which have been developed and refined over decades. Many agree that this is the era of synthetic biology, smarter automation …

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Why is a clonally pure cell line so important in CRISPR research?

Never far from scientific and mainstream news, CRISPR is regularly hailed as one of the most important scientific discoveries of our time. With potential applications across wide-ranging fields from medicine to agriculture, being able to control gene expression could provide treatments for a number of genetic diseases and solve global food shortages in times of …

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Solentim Wins Two Queen’s Awards for Enterprise

Solentim’s business excellence and expertise in cell line development recognised with awards, for both International Trade and Innovation Wimborne, UK, 8th October 2018 / Solentim, a leading provider of instrumentation used by biopharma companies in the fields of mammalian cell line development and cell culture, has received two Queen’s Awards for Enterprise, one for International Trade and one …

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The changing workflows of cell line development – Quality, not Quantity

Damp weather did little to suppress the energy in the rooms at last week’s 10th Annual BioProcessing Summit in Boston. There were over 1,000 delegates, including many from the US West Coast and Europe, all there to listen, learn, and participate in what promised to be a valuable week. With seven parallel sessions running through …

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Technology facilitating single cell cloning to help meet regulatory requirements

Patricia Fitzpatrick Diamond discusses recent technological advances aiding single cell cloning, including Solentim’s VIPS™, in GEN. To meet regulatory standards, recombinant proteins must be produced from a single cell line, demonstrating monoclonality whilst maintaining viability. This is a slow and involved process, with commonly used methods exhibiting significant draw backs. Limiting dilution retains the viability …

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